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Collections of compounds including synthetic molecules, natural products, and extracts; high-throughput screening of compound libraries against isolated, hypothetically disease-modifying biological targets is used to identify possible pharmaceuticals.
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A unique collection of 259 small molecule inhibitors used for MAPK signaling research. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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A unique collection of 2417 small molecules with biological activity used for Immunology/Inflammation research and associated assays. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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MW 248.24 Da. Indoloquinazoline alkaloid with broad pharmacological activity. Immunomodulatory activity. Blocks BV2 microglia activation in response to LPS. Inhibits pro-inflammatory cytockine production via Nrf2, HO-1 and NFκB pathways. Inhibits indoleamine 2,3-dioxygenase 2 (IC₅₀ = 5-17 μM). Promotes neuronal differentiation of human neuroblastoma cells. Also reported to have anti-cancer, anti-microbial and anti-oxidant activity.
MW 248.24 Da. Indoloquinazoline alkaloid with broad pharmacological activity. Immunomodulatory activity. Blocks BV2 microglia activation in response to LPS. Inhibits pro-inflammatory cytockine production via Nrf2, HO-1 and NFκB pathways. Inhibits indoleamine 2,3-dioxygenase 2 (IC₅₀ = 5-17 μM). Promotes neuronal differentiation of human neuroblastoma cells. Also reported to have anti-cancer, anti-microbial and anti-oxidant activity.
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A unique collection of 1099 small molecules used for apoptosis research targeting Bcl-2,Caspase,p53,TNF-alpha,Mdm2,survivin, etc. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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A unique collection of 231 small molecule modulators used for Ion channel research. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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A unique collection of 150 small molecules for exploring the development of diabetes. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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A unique collection of 350 small molecule inhibitors used for PI3K/Akt/mTOR pathway research. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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A unique collection of 561 compounds with biological activity used for stem cell regulatory and signaling pathway research. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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EPO mRNA encodes human erythropoietin (EPO) protein a hormone that regulates erythropoiesis or red blood cell production EPO also plays roles in wound healing and the brain s response to neuronal injury Studies have shown that in vivo transfection with EPO mRNA leads to significant increases in reticulocyte count and hematocrit levels This mRNA utilizes co-transcriptional capping technology to incorporate a Cap 1 structure It is polyadenylated and incorporates UTP modification reducing the immune response in host cells and enhancing mRNA stability and translation efficiency
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