Drug Discovery Research Screening Libraries
AdipoGen 3-4-Aminophenyl-7-diethylam
Chemical. CAS 36840-64-9. Formula C20H22N2O2. MW 322.4. Fluorogenic amine label used for the synthesis of fluorescent reagents. Spectral Data lambdaex = 396nm lambdaem = 480nm in DMF, Lit.
AdipoGen Acetamidofluorescein
Chemical. CAS 82779-14-4. Formula C22H15NO6. MW 389.36. Acetamidofluorescein is a N-acetyl derivative of fluorescein that is strongly fluorescent und used as a fluorescent label. Spectral data lambdaex = 491nm, lambdaem 515nm.
AdipoGen BQ-788 sodium salt
Chemical. CAS 156161-89-6. Formula C34H50N5O7 . Na. MW 640.8 . 23.0. Synthetic. Potent and selective endothelin B receptor ETBR antagonist.
Apexbio Technology LLC DiscoveryProbe™ Bioactive Compound Library, 100uL/well(10 mM solution),96 Well Racks With Screw Cap
3317 bioactive compounds. Other sizes are available. Please inqury us for quote.
Apexbio Technology LLC DiscoveryProbe™ Autophagy Compound Library Plus 100uL/well(10 mM solution),96 Well Deep Well Plate
DiscoveryProbe Autophagy Compound Library is a collection of 486 small molecule compounds carefully selected based on published evidence and experimental validation for their modulatory activity on cellular autophagy pathways Autophagy a conserved cellular process regulated by molecules such as mTOR AMPK ULK1 and Beclin-1 is involved in maintaining cellular homeostasis by mediating the turnover of intracellular components Dysregulation of autophagic pathways contributes to the progression of various human disorders including cancer neurodegeneration and metabolic diseases making this library suitable for biomedical research This library offers compounds approved by regulatory agencies including FDA EMA and CFDA alongside well-characterized experimental tool inhibitors and activators such as rapamycin chloroquine bafilomycin A1 and wortmannin for evaluating autophagic flux in cellular or animal model systems
Apexbio Technology LLC DiscoveryProbe™ GPCR Compound Library, 100uL/well(10 mM solution),96 Well Racks With Screw Cap
A unique collection of 677 GPCR-related small molecules for GPCR screening. Other sizes are available. Please inqury us for quote.
Apexbio Technology LLC DiscoveryProbe™ Cell Cycle Library, 100uL/well(10 mM solution), 96 Well Racks With Screw Cap
A unique collection of 449 cell cycle-related compounds for cell cycle research. Other sizes are available. Please inqury us for quote.
AdipoGen DL-Phenylalanine
Chemical. CAS 150-30-1. Formula C9H11NO2. MW 165.19. Synthetic. Essential alpha-amino acid in humans. Mixture of D-phenylalanine and L-phenylalanine. Precursor for tyrosine, the monoamine neurotransmitters dopamine, norepinephrine noradrenaline, epinephrine adrenaline, the neuromodulator phenethylamine and the skin pigment melanin. Used in the manufacture of food and drink products and sold as a nutritional supplement for its reputed analgesic and antidepressant effects. Building block which may be used by as starting material for synthesis.
Apexbio Technology LLC DiscoveryProbe™ Protease Inhibitor Library, 100uL/well(10 mM solution), 96 Well Racks With Screw Cap
A unique collection of 825 protease inhibitors for high throughput screening (HTS) and high content screening (HCS). Other sizes are available. Please inqury us for quote.
Abcam PNU 74654, Wnt signaling pathway blocker, 5MG
MW 320.3 Da, Purity >98%. Wnt signaling pathway blocker. Inhibits Wnt/β-catenin pathway. Blocks the protein-protein interaction between β-catenin and TCF. Antitumor effects.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen Lac-Phe Acetate
Chemical. CAS 183241-73-8. Formula C12H15NO4 . C2H3O2. MW 237.3 . 59.0. Lac-Phe is an exercise-inducible metabolite, also called exerkine, that suppresses feeding and obesity. Lac-Phe is increased heavily with exercise in mammals and acts to reduce food intake and potentially decrease overall body weight and fat mass. In diet-induced obese mice, pharmacological administration of Lac-Phe led to decreased food intake, adiposity and body weight, as well as improved glucose homeostasis, while movement and energy expenditure were not affected. The biosynthesis of Lac-Phe from lactate and phenylalanine occurs in CNDP2 cells, including macrophages, monocytes and other immune and epithelial cells.
AdipoGen COMP ratAng1 h rec
Protein. The fibrinogen-like domain aa 284-498 of human angiopoietin-1 is fused at the N-terminus to the coiled-coil domain of rat COMP cartilage oligomeric matrix protein and to a FLAG -tag. Source CHO cells. Endotoxin content <0.05EU/µg purified protein LAL test Lonza. Lyophilized. Contains PBS 0.02% CHAPS. Binds to human angiopoietin-1 receptor Tie-2. Purity >95% SDS-PAGE. Soluble, stable and more potent angiopoietin-1 Ang-1 variant.
AdipoGen beta-NAD hydrate
Chemical. CAS 53-84-9. Formula C21H27N7O14P2 . xH2O. MW 663.43 anhydrous basis. NAD, known more formally as nicotinamide adenine dinucleotide, is a signaling molecule as well as a cofactor or substrate for many enzymes. It acts as an oxidizing agent, accepting electrons from other molecules while being converted to its reduced form, NADH. NAD is also essential for the activity of several enzymes, including polyADP-ribose polymerases and cADP-ribose synthases. For example, it is used by some sirtuins to mediate protein deacetylation, producing O-acetyl-ADP-ribose and nicotinamide as well as the deacetylated protein. NAD is an important player and factor to research metabolic pathways and pathologies.
AdipoGen Helvolic acid
Chemical. CAS 29400-42-8. Formula C33H44O8. MW 568.7. Isolated from Aspergillus fumigatus Strain WDMH-35. Steroidal triterpene. Antibiotic. Antibacterial. Shows broad activity against Gram positive and negative bacteria. Mycotoxin. Antifungal. Antitumor agent. Cytotoxic against different human cancer cells. Antituberculosis agent. Oxidized LDL uptake inhibitor. Phytotoxin. Inhibitor of the protein biosynthesis through archeal elongation factor 2 EF-2.